Table 1.

Altered coding transcripts, miRNA and non-coding RNAs in differentiating vs. proliferating keratinocytes and the effect of exposure to atRA and ddRA for 4 and 24 h

	Differentiating vs. proliferating	Differentiating keratinocytes				Proliferating keratinocytes
	24 h	4 h		24 h		4 h		24 h
		atRA vs. vehicle	ddRA vs. vehicle	atRA vs. vehicle	ddRA vs. vehicle	atRA vs. vehicle	ddRA vs. vehicle	atRA vs. vehicle	ddRA vs. vehicle
Induced
>2 FC	424	39	28	86	77	3	3	8	7
1.5–1.99 FC	285	45	55	121	98	4	3	5	8
Transcripts	709	84	83	207	175	7	6	13	15
Suppressed
>2 FC	324	4	5	69	97	0	0	1	1
1.5–1.99 FC	406	11	8	98	107	1	2	5	9
Transcripts	730	15	13	167	204	1	2	6	10

Induced and suppressed transcripts showing a fold change (FC) >2, and transcripts with a fold change in the range 1.5–1.99 are reported in two separate groups

Diff. differentiating keratinocytes, Prol. proliferating keratinocytes, atRA all-trans retinoic acid, ddRA 3,4-didehydroretinoic acid