Table 5.
Group | n |
ERK1/2 |
K-ras |
||||
mRNA | Protein | p-ERK1/2 | mRNA | Protein | p-K-ras | ||
Control group | 5 | 0.76 ± 0.04 | 0.56 ± 0.05 | 0.32 ± 0.02 | 0.54 ± 0.08 | 0.56 ± 0.04 | 0.31 ± 0.05 |
Pentagastrin group | 5 | 0.79 ± 0.05 | 0.60 ± 0.04 | 0.43 ± 0.04a | 0.59 ± 0.06 | 0.57 ± 0.04 | 0.45 ± 0.06a |
Proglumide group | 5 | 0.74 ± 0.06 | 0.55 ± 0.07 | 0.31 ± 0.02c | 0.53 ± 0.05 | 0.55 ± 0.04 | 0.27 ± 0.06c |
Pentagastrin + proglumide group | 5 | 0.77 ± 0.05 | 0.58 ± 0.05 | 0.36 ± 0.01c | 0.55 ± 0.06 | 0.57 ± 0.04 | 0.35 ± 0.04c |
P < 0.05 vs control group;
P < 0.05 vs pentagastrin group. ERK1/2: Extracellular signal-regulated protein kinase 1/2.