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. 2014 Sep 17;9(9):e107860. doi: 10.1371/journal.pone.0107860

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© 2014 Son et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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At the extreme 5′ terminus are two stem-loop structures, labelled domains Ia and Ib. Secondary stem-loops include two smaller stem loop structures labelled Ic and Id. A secondary structure model for the domains II and III of the type IV internal ribosome entry site element is shown (this model is based on previously published studies [9], [29], [30]).