Table 2.
The sensitivity, specificity, and accuracy of diagnostics (ACC) for the main parameters under study.
| Sensitivity (95% CI) | Specificity (95% CI) | ROC curve area (95% CI) | P Value | ACC | |
|---|---|---|---|---|---|
| Anti-TF IgA | 0.68 (0.51–0.82) | 0.77 (0.56–0.91) | 0.70 (0.57–0.83) | 0.007 | 0.719 |
| Anti-TF IgG | 0.55 (0.44–0.67) | 0.58 (0.41–0.74) | 0.53 (80.42–0.65) | 0.543 | 0.563 |
| Anti-TF IgM | 0.66 (0.57–0.75) | 0.69 (0.56–0.81) | 0.69 (0.61–0.77) | <0.0001 | 0.670 |
| SNA | 0.60 (0.51–0.69) | 0.62 (0.49–0.74) | 0.66 (80.58–0.7) | 0.000 | 0.611 |
| SNA/anti-TF IgA | 0.71 (0.54–0.85) | 0.73 (0.52–0.88) | 0.79 (0.67–0.91) | <0.0001 | 0.719 |
| SNA/anti-TF IgG | 0.66 (0.54–0.77) | 0.60 (0.43–0.76) | 0.64 (0.53–0.75) | 0.017 | 0.643 |
| SNA/anti-TF IgM | 0.70 (0.61–0.78) | 0.67 (0.54–0.79) | 0.73 (0.66–0.80) | <0.0001 | 0.692 |
95% CI: 95% confidence interval (in brackets).
ACC: accuracy of diagnostics for each subgroup calculated by the ROC analysis as compared with that of the corresponding subgroup of controls (31 blood donors and 30 patients with nonmalignant gastric diseases). ACC = (TP + TN)/(TP + TN + FP + FN) where TP: true positive cases, TN: true negative cases, FP: false positive cases, and FN: false negative cases.