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. 2014 Sep 17;9(9):e107823. doi: 10.1371/journal.pone.0107823

Figure 2. The inhibition effect of rhEndostatin on the growth of HUVEC in vitro.

Figure 2

HUVECs were planted in fibronectin coated 96-well microtiterplates at 5×10∧3cells per well with bFGF supplemented M199 medium. rhEndostatin was applied at the dosage of 0.1, 0.2, 0.5, 1.0, 2.0, 4.0, 8.0, 16 µg/ml, as described before. All the treatments were triplicated. The OD value were shown as mean ± SD. Treatment with 2 µg/mL of rhEndostatin and above significantly inhibited HUVEC proliferation compared to saline vehicle control.