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GWA mapping using average fold change in liver triglyceride identifies QTLs associated with sensitivity to INH-induced microvesicular steatosis. (A) Manhattan plot of haplotype associations. Black line indicates the threshold for significance, −log10(p) = 3.5. Circled numbers identify the QTL peaks. (B) QTL regions identified by GWA mapping. Plin2 (bold) was selected for further analysis.
