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. 2014 Sep 13;9:36. doi: 10.1186/1750-1326-9-36

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Copyright © 2014 Kang et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Changes in the relative abundances of gut bacteria by HFD or exercise. (A) HFD caused a bloom of OTU115 from the genus Streptococcus that returned to nearly undetectable levels in HFD + exercise mice. Bacterial of phyla Firmicutes (B), Bacteroidetes (C), and Tenericutes (D) of the gut microbiome were significantly altered by both HFD and exercise. Data was analyzed by two-way ANOVA with post-hoc Holm-Sidak t-tests with significance indicated as *p < 0.05, **p < 0.01, ***p < 0.001, and ****p < 0.0001. All data presented as mean +/- SEM from n=10/group.