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In vivo effect of HT29 tumors treatment with Ts29.2 antibodies. (A) Quantification of angiogenesis (CD34 vascular labeling), apoptosis (activated caspase 3 labeling) and proliferation (mitotic index). (B) DAB stained vessels are clearly seen within neighboring tumor areas. (C) The DAB stained cells are easily distinguished from neighboring tumor areas. No difference is seen between the mAb Ts29.2 treated tumor (left) and the PBS treated tumor (right) in (B,C). Scale bar 50 μm.
