Table 1.

Association results for rs9890413 (WNT3/WNT9b) and rs56273700 (MECOM) at all stages of the analysis: discovery, Follow-up 1 and Follow-up 2

SNP	Sample	N		Test, P	OR	EA	MAF
		Cases	Controls				Cases	Controls
rs9890413	Meta GWAS	98	526	Z-score, 8.88 × 10−5
	GWAS1	43	259	LOGISTIC, 0.0239	1.86	G	0.40	0.29
	GWAS2	55	267	LOGISTIC, 0.0013	2.11	G	0.45	0.30
	Follow-up 1	147	339	Z-score, 0.0390
	Germany	94	278	LOGISTIC, 0.0995	1.32	G	0.39	0.32
	Sweden	26	61	LOGISTIC, 0.4915	1.24	G	0.40	0.34
	Spain–Italy	27	N/A	TDT, 0.2752	1.63	G	N/A	N/A
	Follow-up 2	51	N/A	TDT, 0.0095	2.31	G	N/A	N/A
rs56273700	Meta GWAS	98	526	Z-score, 5.15 × 10−5
	GWAS1	43	259	LOGISTIC, 0.0074	0.48	G	0.15	0.28
	GWAS2	55	267	LOGISTIC, 0.0013	0.49	G	0.15	0.29
	Follow-up 1	147	339	Z-score, 0.0317
	Germany	94	278	LOGISTIC, 0.0171	0.62	G	0.22	0.31
	Sweden	26	61	LOGISTIC, 0.2897	0.66	G	0.23	0.31
	Spain–Italy	27	N/A	TDT, 0.4913	1.38	G	N/A	N/A
	Follow-up 2	51	N/A	TDT, 0.0423	0.52	G	N/A	N/A

N, number of cases and controls in study sample (for trio samples, the number of index patients is given in the case column); test, P, test statistic (LOGISTIC, logistic regression; TDT, transmission disequilibrium test) used and P-value for association; EA, effect allele; OR, odds ratio (based on effect allele); MAF, minor allele frequency (same as effect allele for both SNPs, no MAF given for trio samples).