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. 2014 Sep 19;20:1271–1280.

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Copyright © 2014 Molecular Vision.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited, used for non-commercial purposes, and is not altered or transformed.

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Seven days after human retinal progenitor cells were injected into the subretinal space in B6 mice. The first row (A, B, C) shows the Cyclosporin A (CsA)-treated group after injection (n=15). The second row (D, E, F) are the human retinal progenitor cell (hRPC) groups as the control (n=15). G: The average number of cells in the subretinal space was counted per microscopic field. The columns are the mean values, and the error bars are standard deviation (SD). A cluster of hRPCs remained in the subretinal space, and the survival rate decreased for both groups, but still showed a difference (p<0.05; n = 15). Scale bar = 50 μm. Abbreviations: outer nuclear layer (ONL); subretinal space (SRS).