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. Author manuscript; available in PMC: 2015 Sep 17.
Published in final edited form as: Neuron. 2014 Sep 17;83(6):1303–1318. doi: 10.1016/j.neuron.2014.08.029

Figure 1. Developmental sequences producing stereotypic neuronal connectivity patterns.

Figure 1

A. Postsynaptic cells receive a diversity of afferent inputs (convergence), and often, presynaptic cells contact multiple postsynaptic targets (divergence). Adult patterns of synaptic convergence and divergence may be derived from initially imprecise sets of connections that undergo refinement upon maturation. A, B. Biased connectivity can arise from differences in the number of connected presynaptic cells (A, shown here for contacts with two purple cells compared to contact with a single green cell), from differences in the number of synapses (red puncta) made by each axon type (B), or from differences in synaptic strength (not shown). Additionally, different input types could utilize disparate receptor types to achieve differential connectivity.