Table 1. Selection of previously identified risk alleles for psoriasis.
ID | Chr. | Position | Risk allele | Cases risk allele freq. | Controls risk allele freq. | OR | Closest gene |
rs4406273 | 6 | 31266090 | A | 0.259 | 0.092 | 3.45 | WASF5P |
rs34536443 | 19 | 10463118 | G | 0.974 | 0.953 | 1.85 | TYK2 |
rs2233278 | 5 | 150467189 | C | 0.090 | 0.058 | 1.61 | TNIP1 |
rs9988642 | 1 | 67726104 | T | 0.952 | 0.929 | 1.52 | IL23R |
rs33980500 | 6 | 111913262 | T | 0.108 | 0.074 | 1.52 | TRAF3IP2 |
rs12188300 | 5 | 158829527 | T | 0.132 | 0.095 | 1.45 | IL12B |
Shown are the SNP IDs, chromosome, position, risk allele frequencies [14], odds ratio (OR), and closest gene for all markers cited by Tsoi et al. [14] with an OR of at least 1.4. Positions follow Genome Build 37.3, as given by NCBI's dbSNP website (http://www.ncbi.nlm.nih.gov/projects/SNP/).