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. Author manuscript; available in PMC: 2014 Sep 19.
Published in final edited form as: JAMA. 2011 Oct 12;306(14):1549–1556. doi: 10.1001/jama.2011.1437

Table 3. Number and risk of prostate cancers.

Placebo
(n=8,696)
Vitamin E alone
(n=8,737)
Selenium alone
(n=8,752)
Vitamin E + selenium
(n=8,702)
Number of prostate cancers
 As of 10/2008 416 473 432 437
 As of 07/2011 529 620 575 555
Hazard ratio, (99% CI), p-value
 As of 10/2008 1.13 (0.95 – 1.35), p=.06 1.05 (0.88 – 1.25), p=.52 1.04 (0.87 – 1.24), p=.62
 As of 07/2011 1.17 (1.004 – 1.36), p=.008 1.09 (0.93 – 1.27), 0=.18 1.05 (0.89 – 1.22), p=.46
Absolute risk 9.3 10.9 10.1 9.7
Gleason ≥ 7 (n) 133 155 161 164
Hazard ratio (99% CI), p-value 1.16 (0.86, 1.58), p=.20 1.21 (0.90, 1.63), p=.11 1.23 (0.91, 1.66), p=.08

Prostate cancers per 1,000 person years

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