Table 3. Number and risk of prostate cancers.
Placebo (n=8,696) |
Vitamin E alone (n=8,737) |
Selenium alone (n=8,752) |
Vitamin E + selenium (n=8,702) |
|
---|---|---|---|---|
Number of prostate cancers | ||||
As of 10/2008 | 416 | 473 | 432 | 437 |
As of 07/2011 | 529 | 620 | 575 | 555 |
Hazard ratio, (99% CI), p-value | ||||
As of 10/2008 | 1.13 (0.95 – 1.35), p=.06 | 1.05 (0.88 – 1.25), p=.52 | 1.04 (0.87 – 1.24), p=.62 | |
As of 07/2011 | 1.17 (1.004 – 1.36), p=.008 | 1.09 (0.93 – 1.27), 0=.18 | 1.05 (0.89 – 1.22), p=.46 | |
Absolute risk† | 9.3 | 10.9 | 10.1 | 9.7 |
Gleason ≥ 7 (n) | 133 | 155 | 161 | 164 |
Hazard ratio (99% CI), p-value | 1.16 (0.86, 1.58), p=.20 | 1.21 (0.90, 1.63), p=.11 | 1.23 (0.91, 1.66), p=.08 |
Prostate cancers per 1,000 person years