Table 1. Univariate analysis of clinicopathological factors regarding overall survival (OS) in proximal colon cancer.

Variable	OS
	na	Events	P valueb
Clinicopathological factors:
Tumor size
pT0–2	28	2	0.206
pT3–4	119	27
Lymph node status
pN neg	89	12	0.003
pN1–3	58	17
Tumor stage
stage 1–2	125	20	<0.001
stage 3–4	15	8
CIMP status
Non-CIMP	23	5	0.806
CIMP	117	23
Microsatellite status
MSS	82	16	0.440
MSI	60	12
ITIH5 (median expression)
≤329	74	20	0.049
>329	74	9

MSS, Microsatellite stable; MSI-L, Microsatellite instable low; MSI-H, Microsatellite instable high, CIMP-L, CpG island methylator phenotype low, CIMP-H, CpG island methylator phenotype high, ITIH, inter-a-trypsin inhibitor heavy chain. Significant P values marked in bold face. ^aOnly patients with primary, proximal colon cancer were included. ^bBreslow test at the two-sided significance level of 0.05