Table 3. Binding affinity of λ and λ engineering mutants. The EC50 values for receptor X were determined in a receptor X down ELISA. The reported values are representative to two other repeated measurements.
Antibody | λ | λdS | λ P210R | λ A211G |
---|---|---|---|---|
Receptor X binding EC50 (nM) |
0.63 | 0.57 | 0.95 | 0.71 |