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. Author manuscript; available in PMC: 2014 Sep 19.
Published in final edited form as: Analyst. 2011 Mar 4;136(17):3557–3565. doi: 10.1039/c0an00854k

Figure 7.

Figure 7

Measurements of endogenous serotonin in Drosophila. (A) Effect of COOH-CNT modification on the detection of 10 μM serotonin using the “serotonin waveform.” Electrode was scanned from 0.2 to 1.0 to −0.1 and back to 0.2 V at 1000 V/s at 10 Hz. The CV compares an electrode before (dashed) and after (solid) CNT modification during in vitro calibration. The inset shows average sensitivity for the oxidation peak (n=5). (B) Detection of serotonin in a larval Drosophila melanogaster ventral nerve cord. Different nerve cords are used for the bare (dashed) and COOH-CNT (solid) electrodes. Converting current to concentration using calibration data shows the COOH-CNT detected 650 nM serotonin with a peak oxidation current of 0.54 nA, while the bare electrode detected 870 nM serotonin with a peak oxidation current of 0.33 nA. The inset shows the average sensitivity for bare electrodes and COOH-CNT modified electrodes in Drosophila (n=5).