Table 4.
Genes displaying sexually dimorphic expression and exhibiting a role in epigenetic processes
| Symbol | FC-SI | FC-Colon | Description | Chr | Epigenetic activity |
|---|---|---|---|---|---|
| Mbd1 |
−1.13♂ |
−1.03 |
Methyl-CpG-binding domain protein 1 |
18 |
Binding to methylated DNA |
| Phf20 |
1.02 |
−1.14♂ |
PHD finger protein 20 |
2 |
Histone acetylation |
| Uty |
−48.21♂ |
−44.48♂ |
Ubiqu. transcribed tetratricopeptide repeat gene, Y chr |
Y |
Histone demethylation |
| Kdm5d |
−15.67♂ |
−21.58♂ |
Lysine (K)-specific demethylase 5D |
Y |
Histone demethylation |
| Kdm6a |
1.59♀ |
1.57♀ |
Lysine (K)-specific demethylase 6A |
X |
Histone demethylation |
| Kdm5c |
1.32♀ |
1.28♀ |
Lysine (K)-specific demethylase 5C |
X |
Histone demethylation |
| Bcorl1 |
1.15♀ |
1.04 |
BCL6 co-repressor-like 1 |
X |
Associates with HDAC activity |
| Hdac11 |
1.14♀ |
−1.11 |
Histone deacetylase 11 |
6 |
Histone deacetylation |
| Piwil4 | 1.17♀ | −1.03 | Piwi-like RNA-mediated gene silencing 4 | 9 | Histone methylation |
♂Significant ♂-dominant expression; ♀significant ♀-dominant expression.