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. Author manuscript; available in PMC: 2015 Sep 1.
Published in final edited form as: Biomaterials. 2014 Jun 24;35(28):8049–8064. doi: 10.1016/j.biomaterials.2014.05.084

Fig. 9.

Fig. 9

Assessment of total IBA1+ immunoreactivity surrounding intracortical microelectrodes over time. Highest levels of IBA1+ immunoreactivity was observed at two and sixteen weeks post implantation, with significantly lower IBA1+ immunoreactivity observed at eight weeks post implantation (A–E). Co-localization of CFP+ and IBA1+ immunoreactivity within the total IBA1+ population demonstrated that less than 20% of the IBA1+ population were comprised of resident microglia at two weeks, while 40% of IBA1+ population was comprised of resident microglia by sixteen weeks (F/G). scale bar = 100 μm; significance p < 0.05; n = 4–7 per cohort.