Fig. 8.

Acute estradiol treatment does not alter sensorimotor performance. (A) Locomotor activity was assessed as the number of grid crosses. (B) Exploration was assessed as the number of rears. (C) Anxiety-like behavior was assessed as the time (s) spent in the center of the open field. (D) Object exploration was assessed as the average time (s) spent exploring both objects in Trial 1 of the object placement and object recognition tests. Open field tests were of 6-min duration, and trials in the object placement and object recognition tasks were of 3-min duration. Estradiol did not significantly alter sensorimotor performance in any tests examined. Samples sizes are denoted on individual bars in panel A and are the same for panels A–D. Data are expressed as X ± SEM.