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. Author manuscript; available in PMC: 2014 Sep 19.
Published in final edited form as: Sci Transl Med. 2012 Feb 8;4(120):120ra15. doi: 10.1126/scitranslmed.3002865

Fig. 6.

Fig. 6

fMRI results for initially injected eyes 90 days after readministration of the contralateral eyes. (A and B) CH12’s fMRI results to high- and medium-contrast stimuli demonstrated significant bilateral cortical activation. (C and D) CH11 also showed widespread activation for high- and medium-contrast stimuli. (E and F) Although NP01 also showed activation in response to the high- and medium-contrast stimuli, they were at an uncorrected statistical threshold. Lower activation in NP01 may be due to a lower dose of AAV2-hRPE65v2 for the initial subretinal injection and the fact that this subject is a chronic smoker.