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. 2014 Oct;75:76–87. doi: 10.1016/j.yjmcc.2014.07.008

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© 2014 The Authors. Published by Elsevier Ltd.

This work is licensed under a Creative Commons Attribution 3.0 Unported License.

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Fig. 6 — Cardiac phenotype in adult MCD^−/− mice. (A) Assessment of cardiac hypertrophy at morphological and molecular level; (B) mRNA levels of cardiac hypertrophic markers (n = 9 per group). (C) Relationship between LV weight (MCD^−/− r = − 0.83, P = 0.005; MCD^+/+ r = 0.31, P = 0.42) and (D) contractility (MCD^−/− r = 0.36, P = 0.34; MCD^+/+ r = – 0.82, P = 0.007) versus age. (E) Metabolic (triglyceride) and (F) energetic (total adenine nucleotide pool) profile of MCD surviving adult mice (n = 5–9 per group). (G) Representative M-mode ultrasound images obtained from the parasternal short-axis view in MCD adult mice.