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. Author manuscript; available in PMC: 2014 Sep 19.
Published in final edited form as: Cochrane Database Syst Rev. 2010 Nov 10;(11):CD006633. doi: 10.1002/14651858.CD006633.pub2

Comparison 2. CLOZAPINE versus OLANZAPINE - Sensitivity Analysis.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Mental state: 1a. PANSS total score, excluding possibly skewed data (high = poor) 5 577 Mean Difference (IV, Random, 95% CI) 2.16 [−1.23, 5.54]
 1.1 short term 1 74 Mean Difference (IV, Random, 95% CI) 2.44 [−3.10, 7.98]
 1.2 medium term 4 503 Mean Difference (IV, Random, 95% CI) 1.99 [−2.29, 6.27]
2 Mental state: 1b. BPRS-18 (1-7) total score, excluding possibly skewed data (high = poor) 3 204 Mean Difference (IV, Random, 95% CI) 1.12 [−3.03, 5.27]
 2.1 short term 2 28 Mean Difference (IV, Random, 95% CI) 0.32 [−8.74, 9.38]
 2.2 medium term 1 176 Mean Difference (IV, Random, 95% CI) 1.20 [−3.03, 5.43]
3 Mental state: 2a. PANSS positive subscore, excluding possibly skewed data (high = poor) 5 577 Mean Difference (IV, Random, 95% CI) 0.34 [−0.77, 1.44]
 3.1 short term 1 74 Mean Difference (IV, Random, 95% CI) −0.13 [−2.12, 1.86]
 3.2 medium term 503 Mean Difference (IV, Random, 95% CI) 0.54 [−0.78, 1.87]
4 Mental state: 2b. BPRS positive subscore, excluding possibly skewed data (high = poor) 1 13 Mean Difference (IV, Random, 95% CI) −1.11 [−4.32, 2.10]
5 Mental state: 3. SANS, excluding possibly skewed data (high=poor) 1 25 Mean Difference (IV, Random, 95% CI) −11.0 [−20.90, −1.10]