Comparison 8. CLOZAPINE versus ZOTEPINE.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Leaving the study early: any reason	1	50	Risk Ratio (M-H, Random, 95% CI)	0.7 [0.32, 1.54]
2 Global state: no clinically important change - less than successfully and no increase on CGI-S - short term	1	59	Risk Ratio (M-H, Random, 95% CI)	0.12 [0.02, 0.87]
3 Mental state: BPRS-18 total score - short term (high=poor)	1	59	Mean Difference (IV, Random, 95% CI)	−6.0 [−9.83, −2.17]
4 Adverse effects: 1. Extrapyramidal: antiparkinson medication use - short term	1	59	Risk Ratio (M-H, Random, 95% CI)	0.05 [0.00, 0.86]
5 Adverse effects: 2. Prolactin: average change - short term (high=poor)	1	59	Mean Difference (IV, Random, 95% CI)	−33.4 [−48.67, −18.13]