Table 2.
Normal diastolic function‡ (n = 62) | Diastolic dysfunction‡ (n = 62) | P | |
---|---|---|---|
CMR mitral annulus sweep volume | |||
Normalized peak sweep rate, early diastole (PSRE), s−1 | 7.72 ± 1.7 | 5.25 ± 1.38 | <0.001* |
Peak sweep rate, early diastole, cm3/s | 117 ± 43 | 65 ± 28 | <0.001* |
Normalized peak sweep rate, atrial systole (PSRA), s−1 | 4.67 ± 1.38 | 6.56 ± 1.99 | <0.001* |
Peak sweep rate, atrial systole, cm3/s | 70 ± 24 | 80 ± 29 | 0.031* |
PSRE/PSRA ratio | 1.82 ± 0.69 | 0.9 ± 0.44 | <0.001* |
Percentage sweep volume recovery, early diastole | 69.09 ± 10.02 | 54.29 ± 12.37 | <0.001* |
Absolute sweep volume, early diastole, cm3 | 10.64 ± 4.1 | 6.83 ± 2.66 | <0.001* |
Absolute sweep volume/stroke volume, early diastole, % | 11.17 ± 2.89 | 7.6 ± 2.21 | <0.001* |
Percentage sweep volume recovery, atrial systole | 33.78 ± 9.92 | 49.1 ± 13.76 | <0.001* |
Absolute sweep volume, atrial systole, cm3 | 5.03 ± 1.72 | 6.01 ± 2.35 | 0.014* |
Absolute sweep volume/stroke volume, atrial systole, % | 5.41 ± 1.78 | 6.81 ± 2.24 | 0.014* |
Normalized average sweep rate, early diastole, s−1 | 4.2 ± 1.02 | 2.53 ± 0.63 | <0.001* |
Normalized average sweep rate, mid-diastole, s−1 | 0.36 ± 0.71 | 0.87 ± 1.34 | 0.019* |
Normalized average sweep rate, atrial systole, s−1 | 2.67 ± 0.94 | 3.88 ± 1.26 | <0.001* |
Sweep volume deceleration time (DTSV), ms | 96.25 ± 36.56 | 144.19 ± 54.89 | <0.001* |
Sweep volume acceleration time (ATSV), ms | 102.48 ± 35.03 | 114.2 ± 41.09 | 0.066† |
50% Diastolic sweep volume recovery time (DSVRT50), % | 15.58 ± 4 | 24.97 ± 11.03 | <0.001* |
Echocardiography | |||
E, cm/s | 84.47 ± 22.22 | 75.81 ± 25.08 | 0.020* |
A, cm/s | 59.45 ± 17.75 | 69.9 ± 22.7 | 0.005* |
E/A | 1.51 ± 0.51 | 1.22 ± 0.67 | <0.001* |
Deceleration time, ms | 219 ± 48 | 230 ± 47 | 0.200 |
e′ septal, cm/s | 10.14 ± 2.22 | 6.05 ± 1.4 | <0.001* |
a′ septal, cm/s | 8.25 ± 1.89 | 8.98 ± 2.44 | 0.064† |
e′/a′ septal | 1.3 ± 0.41 | 0.75 ± 0.34 | <0.001* |
e′ lateral, cm/s | 14.59 ± 3.95 | 8.1 ± 2.56 | <0.001* |
a′ lateral, cm/s | 9.51 ± 2.95 | 10.4 ± 3.75 | 0.141 |
e′/a′ lateral | 1.7 ± 0.71 | 0.89 ± 0.44 | <0.001* |
E/e′ (average) | 7.1 ± 2.02 | 11.47 ± 6.26 | <0.001* |
Data expressed as mean ± SD.
Peak and average sweep rates were normalized to end-systolic sweep volume. Percentage sweep volume recovery measured the proportion of recovery in reference to end-systolic sweep volume. 50% diastolic sweep volume recovery time was normalized to RR interval.
E = peak early mitral inflow velocity; A = peak late mitral inflow velocity; e′ = early diastolic mitral annular velocity; a′ = late diastolic mitral annular velocity; MA = mitral annulus.
*P < 0.05, †P < 0.10, ‡Patient classification based on echocardiography reference.