(A) Stereodiagram of the β-sandwich domain D3 of HK3 BT4673S. Coloring is based on the conservation of residues through all HK3 homologs in B. thetaiotaomicron using the ConSurf scheme [73] whereby degree of conservation are reflected in increasing saturations of purple and degree of variability is reflected in increase saturations of cyan. The figure was generated using PyMol [69].
(B) Topology diagram of HK3 domain D3, opened as a book to view the two sheets from inside the β-sandwich.
(C) Topology diagram of tenascin (modified from [37]).