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. Author manuscript; available in PMC: 2015 Oct 1.
Published in final edited form as: Biochim Biophys Acta. 2014 Jul 5;1841(10):1403–1412. doi: 10.1016/j.bbalip.2014.06.012

Figure 1. S1P/S1PR1-signaling.

Figure 1

In response to S1P, the S1PR1 signaling pathway may increase endothelial barrier function by stimulating actin-dependent outward spreading of endothelial cells and suppressing cellular contractility. Arrows, induction; bar-headed lines, inhibition.