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. Author manuscript; available in PMC: 2015 Oct 21.
Published in final edited form as: Chem Commun (Camb). 2014 Oct 21;50(82):12293–12296. doi: 10.1039/c4cc05901h

Table 3.

Scope of Propargylic Alcohols 9a

Entry Substrate
graphic file with name nihms625527u1.jpg
Product
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Yield (%)b
1 11a, R = nBu 12a 72
2 11b, R = iPr 12b 83
3 11c, R = Ph 12c 42
4 graphic file with name nihms625527t19.jpg
11d
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12d
60
5 graphic file with name nihms625527t21.jpg
11e
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13
63c
a

Conditions: 9 (1 equiv), indole 8a (2 equiv), Cu(CH3CN)4PF6 (10 mol %), 60 °C, ClCH2CH2Cl.

b

Isolated yield.

c

Indole 8b was employed.