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. Author manuscript; available in PMC: 2015 Sep 1.
Published in final edited form as: Pharm Res. 2014 Mar 19;31(9):2490–2502. doi: 10.1007/s11095-014-1345-z

Table IV.

Platinum and ceramide combination index (CI) against SKOV3 ovarian cancer cells

Combination Type SKOV3
CI Interaction type
Cisplatin/C6-ceramide 0.46 Synergetic
Myrisplatin/C6-ceramide NE (NT) 0.86 Synergetic
Myrisplatin/C6-ceramide NE (T) 0.80 Synergetic

CI<1, synergetic; CI = 1, additive; CI > 1, antagonistic