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. 2014 Sep 18;10(9):e1004640. doi: 10.1371/journal.pgen.1004640

Figure 2. Mutation study with an SCS element.

Figure 2

A. Two G to T substitution mutations introduced into a region overlapping seven SCS elements. Positions subjected to substitution mutations are shown in red. B. TR formation patterns compared between the wild type and the mutated penA. C. TRs formed in the mutated penA gene. M-TRs 1 to 8 that were newly formed in the mutated gene and TR10′, a version of TR10 in the wild type gene (Figure 1A), are shown. Common SCSs for M-TRs 3 to 8 are denoted with red arrows.