Table 1. Bivariate analysis of IL28B polymorphisms and HTLV-1-associated myelopathy.
| Characteristic | Total N(%) | Asymptomatic N(%) | HAM/TSP N(%) | OR (95%CI) | P Value |
| Male | 75(32.75) | 45 (33.0) | 30 (38.8) | - | - |
| Female | 154 (67.25) | 91 (67.00) | 63 (61.2) | 1.083 (0.5916–1.823) | 0.99 |
| Age>50 years | 142 (62.01) | 76 (55.9) | 66 (71.0) | 1.93 (1.101–3.383) | 0.03 |
| Age≤50 years | 87 (37.99) | 60 (44.1) | 27 (29.0) | - | - |
| HTLV-1 DNA proviral Load | |||||
| <200 | 142 (62.01) | 99 (72.8) | 43 (46.2) | - | - |
| ≥200 | 87 (37.99) | 37 (27.2) | 50 (53.8) | 3.11 (1.785–5.423) | <0.01 |
| SNP rs12979860 * | |||||
| CC | 68 (30.49) | 48 (36.9) | 20 (21.5) | 1 | |
| CT | 139 (62.33) | 69 (53.1) | 70 (75.3) | 2.45 (1.22–4.93) | 0.01 |
| TT | 16 (7.17) | 13 (10.0) | 03 (3.2) | 0.41 (0.08–2.09) | 0.28 |
| SNP rs8099917 ** | |||||
| TT | 144 (64.00) | 90 (68.2) | 54 (58.1) | 1 | |
| TG | 63 (28.00) | 40 (30.3) | 23 (24.7) | 0.64 (0.33–1.23) | 0.18 |
| GG | 18 (8.00) | 02 (1.5) | 16 (17.2) | 7.00 (1.92–25.4) | <0.01 |
SNP: Single nucleotide polymorphism.
*Four patients without enough samples for IL28b rs8099917 assay.
**Six patients without enough samples for IL28b rs12979860 assay.