Table 4. Univariate association between additional retrospectively analyzed genotypes and tumor response (PR: partial response and SD: stable disease).

Gene	Genotype	Tumor response				P-valuea
		PR (N = 9)		SD (N = 11)
		No.	%	No.	%
TYMS	5′-UTR TSER + G>C (rs34743033)
	TSER*2/*2	5	56	1	9
	TSER*2/*3(G)	2	22	4	36
	TSER*2/*3(C)	2	22	6	55	0.137
TYMS	3′-UTR 1494delTTAAAG(6 bp) (rs34489327)
	+6 bp/+6 bp	5	56	6	55
	+6 bp/−6 bp	4	44	5	45	1
ERCC1	c.354C>T (rs11615)
	C/C	2	22	1	9
	C/T	4	45	8	73
	T/T	3	33	2	18	0.552
ERCC2	c.2251A>C (rs13181)
	A/A	5	56	3	27
	A/C	3	33	6	55
	C/C	1	11	2	18	0.485
GSTP1	c.313A>G (rs1695)
	A/A	4	45	8	73
	A/G	3	33	2	18
	G/G	2	22	1	9	0.552
XRCC1	c.1196G>A (rs25487)
	A/A	1	11	6	55
	G/A	6	67	5	45
	G/G	2	22	0	-	0.050
MDR1	c.3435C>T (rs1045642)
	C/C	0	-	1	9
	C/T	9	100	6	55
	T/T	0	-	4	36	0.056

^aCalculated using Fisher’s exact test.