Table 1. Baseline Characteristics of the nine populations.
AREDS | KORA | FES | MESA | OGP-TALANA | RS1 | RS2 | RS3 | ERF | Total | |
N | 1877 | 1869 | 1389 | 1462 | 683 | 5238 | 2009 | 1970 | 2028 | 18525 |
Mean Age (SD) | 68.0 (4.7) | 55.6 (11.8) | 55.6 (8.9) | 61.9 (9.4) | 42.2 (19.1) | 68.5 (8.6) | 64.2 (7.4) | 60.8 (5.5) | 48.5 (14.3) | |
N Myopia1 Cases | 346 | 550 | 348 | 486 | 71 | 763 | 395 | 594 | 370 | 3923 |
Myopia Cases MSE2 | −2.81 | −2.72 | −3.08 | −3.20 | −4.41 | −3.21 | −3.08 | −3.22 | −3.03 | |
N Myopia Controls | 1333 | 840 | 773 | 731 | 428 | 3964 | 1374 | 1056 | 1197 | 11696 |
Myopia Controls MSE2 | 1.59 | 1.38 | 1.60 | 1.70 | 1.38 | 1.88 | 1.72 | 1.39 | 1.24 | |
N Myopia Unknown | 198 | 479 | 268 | 245 | 184 | 601 | 240 | 320 | 461 | |
N Hyperopia3 Cases | 854 | 424 | 426 | 506 | 64 | 2779 | 919 | 556 | 540 | 7068 |
Hyperopia Cases MSE2 | 2.56 | 2.30 | 2.31 | 2.21 | 2.42 | 2.48 | 2.33 | 2.23 | 2.29 | |
N Hyperopia Controls | 600 | 1010 | 654 | 714 | 153 | 1350 | 627 | 907 | 829 | 6844 |
Hyperopia Controls MSE2 | −1.76 | −1.79 | −1.92 | −2.32 | −2.56 | −2.00 | −2.09 | −2.21 | −1.52 | |
N Hyperopia Unknown | 423 | 435 | 309 | 242 | 466 | 1109 | 463 | 507 | 659 | |
Sex (% Male) (Myopia/Hyperopia) | 41/40 | 50/49 | 42/41 | 54/43 | 41/40 | 48/39 | 49/44 | 46/43 | 53/62 | |
Myopia λ | 1.001 | 0.997 | 1.004 | 1.024 | 1.085 | 1.020 | 1.018 | 1.015 | 1.323 | 1.038 |
Hyperopia λ | 1.020 | 1.023 | 0.997 | 1.017 | 1.156 | 1.041 | 1.024 | 1.010 | 1.254 | 1.046 |
1. For myopia, cases were defined as MSE <−1D, controls>0D and individuals between 0D and −1D coded as unknown.
2. Average MSE of all cases or controls used in the analyses.
3. For hyperopia, cases were defined as MSE>+1D, controls <0D and individuals between 0D and +1D coded as unknown.