Table 3. Multivariate analyses of survival prognostic factors.
| Population 1 (n = 399) | |||
| HR (95% CI) | p (%inclusion) | ||
| Age (years) | |||
| ≤50 | .. | 0.006 (92) | |
| 51–60 | 1.3 (1.1–1.6) | .. | |
| >60 | .. | .. | |
| Karnofsky performance status (%) | |||
| ≤70 | 1.0 | <0.001 (99) | |
| >70 | 0.4 (0.2–0.6) | .. | |
| Extent of surgery | |||
| Biopsy | .. | <0.001 (98) | |
| Partial resection | 0.6 (0.5–0.8) | .. | |
| Complete resection | .. | .. | |
| IDH1 mutational status | |||
| Mutated | 1.0 | 0.02 (94) | |
| Wild-type | 4.1 (1.3–13.3) | .. | |
| MGMT methylation status | |||
| Methylated | 1.0 | <0.001 (100) | |
| Unmethylated | 3.0 (2.2–4.2) | .. | |
| DGKI methylation status | |||
| Methylated | 1.0 | 0.03 (74) | |
| Unmethylated | 0.7 (0.5–1.0) | .. | |
NA = not available; N = not enough events to calculate upper 95% CI boundary; NS = not significant. For ordered categorical factors, the first value is the reference.