Figure 6. Combinatory treatment of fucoidan and salubrinal enhances eIF2α phosphorylation and CHOP expression in MDA-MB-231 cells and HCT116 cells.

Cells were treated with salubrinal (50 µM) alone or in combination with fucoidan (100 µg/ml) for 48 h. Cell lysates (30 µg) were applied for the analysis of the expression of p-eIF2α and CHOP by immunoblot. **p<0.01; ***p<0.001.