Table 2. Mean ancestry fraction and 95% CIs in controls, adenomas, adenocarcinomas and admixed population (MEX and ASW) included into the analysis.
Ancestry fraction | |||
---|---|---|---|
European | Amerindiana | African | |
Group/population |
Mean (95% CI) |
Mean (95% CI) |
Meanb
(95% CI) |
Controls (n=238) | 0.39 (0.38–0.41) | 0.45 (0.43–0.46) | 0.11 (0.10–0.12) |
Adenoma (n=115) | 0.44*** (0.42–0.46) | 0.39*** (0.37–0.41) | 0.13* (0.11–0.15) |
Cancer (n=190) | 0.38 (0.37–0.40) | 0.43 (0.41–0.45) | 0.14** (0.12–0.16) |
MEX (n=77) | 0.48 (0.45–0.51) | 0.48 (0.45–0.51) | 0.04 (0.03–0.05) |
Ref valuec | 0.5 | 0.45 | 0.05 |
ASW (n=83) | 0.18 (0.15–0.20) | 0.05 (0.04–0.07) | 0.77 (0.75–0.79) |
Ref valuec | 0.2 | − | 0.8 |
Abbreviations: ANOVA, analysis of variance; ASW, African ancestry in Southwest USA; CHB, Han Chinese in Beijing, China; CI, confidence interval; MEX, Mexican ancestry from Los Angeles.
P-value for one-way ANOVA test: ***<0.001, **<0.01 and *<0.1*.
Based on CHB reference population.
Back transformated from log.
Seldin et al.27