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. 2014 Sep 19;9(9):e107732. doi: 10.1371/journal.pone.0107732

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© 2014 Vegezzi et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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qRT-PCR analysis shows that T2R138 mRNA and α-gustducin mRNA levels are significantly (*p<0.05; **p<0.01) up-regulated in the colon, but not ileum by a long term (8 weeks) high fat (45% and 60%) diet compared to low (10%) fat diet. By contrast, T2R108 mRNA was not affected by this diet.