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. 2014 Sep 19;9(9):e107913. doi: 10.1371/journal.pone.0107913

Table 3. Proteomic results: increased.

Accession Gene Symbol Protein description KO/WT
Protein synthesis
P60843 Eif4a1 Eukaryotic initiation factor 4A–I 99.083
P62849 Rps24 40 S ribosomal protein S24 36.644
P62908 Rps3 40 S ribosomal protein S3 9.036
P14148 Rpl7 60 S ribosomal protein L7 5.495
P47963 Rpl13 60 S ribosomal protein L13 1.770
Protein/amino acid catabolism
P46471 Psmc2 26 S protease regulatory subunit 7 83.176
Q9QXF8 Gnmt Glycine N-methyltransferase 4.285
Q8QZR5 Gpt Alanine amino transferase 1 1.820
Carbohydrate catabolism
A2AJL3 Fggy FGGY carbohydrate kinase domain containing protein 84.723
Q91×44 Gckr Glucokinase regulatory protein 1.977
Electron transfer/energy production
P03930 Mtatp8 ATP synthase protein 8 9.462
Q9D0M3 Cyc1 Cytochrome c1 6.668
Biotransformation/xenobiotics metabolism
P24456 Cyp2d10 Cytochrome P450 2D10 11.803
P37040 Por NADPH–cytochrome P450 reductase 7.447
Q9DBG1 Cyp27a1 Sterol 26-hydroxylase 4.656
Q9DCM2 Gstk1 Glutathione S-transferase kappa 1 3.467
Hepatocyte structure maintenance
P11679 Krt8 Keratin, type II cytoskeletal 8 12.474
P05784 Krt18 Keratin 5.649
Transport/signaling/chromosome
Q00724 Rbp4 Retinol-binding protein 4 84.723
P29391 Ftl1 Ferritin light chain 1 9.727
P60766 Cdc42 Cell division control protein 42 homolog 2.938
Q64374 Rgn Regucalcin 1.542
P62806 Hist1h4a Histone H4 4.699

The proteins whose levels are increased in CYP2E1 knockout versus wild type (WT) mice and directly related to carbohydrate, protein or amino acid catabolism, or biotransformation are listed. The relative protein expression level in knockout versus wild-type mice (KO/WT) is shown.