Table 1.
Baseline characteristics of COPD subjects included in the meta-analysis
| COPDGene | ECLIPSE | GenKOLS | |
|---|---|---|---|
| N | 2,653 | 1,464 | 426 |
| Age, yrs | 64.7 (8.2) | 63.5 (7.0) | 64.3 (9.3) |
| Sex, male % | 56.0 | 65.8 | 62.9 |
| Current smoker, % | 34.9 | 35.2 | 50.2 |
| Pack-years of cigarette smoking | 56.2 (27.9) | 49.7 (26.7) | 30.9 (18.2) |
| Height, cm | 169.7 (9.4) | 169.4 (9.0) | 170.7 (8.7) |
| Body mass index, kg/m2 | 28 (6.1) | 26.6 (5.6) | 25.6 (4.8) |
| FEV1 % predicted | 50 (17.9) | 47.4 (15.5) | 52.4 (17.0) |
| FVC % predicted | 76.5 (17.0) | 86.0 (19.9) | 80.0 (15.3) |
| FEV1/FVC | 0.49 (0.13) | 0.44 (0.11) | 0.52 (0.12) |
| Total lung capacity (TLC)CT, L | 6.19 (1.4) | 6.20 (1.44) | 5.57 (1.29) |
| TLC % predicted | 102.8 (16.6) | 101.7 (18.2) | 90.9 (18.8) |
Data are presented as mean (SD) or percentage, as appropriate.