Table 2.

Assessments in The DOMUS study

	Investigators	Patient	Caregiver	Bereaved a
Medical History	• Cancer Diagnosis, Co-morbidity, Time of Cancer Diagnosis, Current Disease Stage, ECOG Performance Status etc.	Baseline
Reported Outcomes (questionnaires)	• Relationship Status, Children, Education	Baseline	Baseline
	• Wishes for place of care and treatment	Baseline	Baseline
		Week 2,4,8	Week 2,4,8
		6 months	6 months
	• Quality of life questionnaire – Core (EORTC-QLQ-C30) [34]	Baseline
		Week 2,4,8
		6 months
	• Edmonton Symptom Assessment System (revised version) (ESAS-r) [35]	Baseline
		Week 2,4,8
		6 months
	• Hospital Anxiety and Depression Scale (HADS) [36]	Baseline
		Week 2,4,8
		6 months
	• Symptoms priority	Baseline
		Week 2,4,8
		6 months
	• Symptom Checklist-92, anxiety and depression subscales (SCL-92) [37]	Baseline	Baseline	Week 2
		Week 2,4,8	Week 2,4,8	2, 7, 13, 19 months
		6 months	6 months
	• Modified Medical Outcomes Study Social Support Survey (mMOS-SS)b[38]	Baseline	Baseline	Week 2
				2, 7, 13, 19 months
	• Dyadic Coping Inventory (selected subscales) (DCI)b[39]	Baseline	Baseline
		Week 2,4,8	Week 2,4,8
		6 months	6 months
	• Relationship ladderb[40]	Baseline	Baseline
		Week 2,4,8
		6 months
	• Zarit Burden Interview (ZBI) [41]		Baseline
			Week 2,4,8
			6 months
	• Experiences in Close Relationships-Short Form (ECR) [42]		Baseline	7, 13, 19 months
	• Medical Outcomes Study Short Form (SF-36) [43]		Baseline	Week 2
			Week 2,4,8	2, 7, 13, 19 months
			6 months
	• Inventory of Daily Widowed Life (IDWL) [44]			Week 2
				2, 7, 13, 19 months
	• Pittsburgh Sleep Quality Index (PSQI) [45]			Week 2
				2, 7, 13, 19 months
	• Prolonged Grief Disorder (PG – 13) [46]			7, 13, 19 months
	• Lifestyle single items			Week 2
				2, 7, 13, 19 months
Blood samples	• Telomere length		Baseline	2 months
Databasesc	• Number of hospital admissions	From Baseline to 6 months	From Baseline to 6 months
	• Number of inpatient bed days
	• Number of outpatient visits to hospitals
	• Number of visits to GP
	• Number of visits to the emergency room
	• Number of visits to the emergency physician
	• Number of visits to specialists
	• Treatments in public hospitals
	• Prescribed drugs
	• Place of care and death
Healthcare services	• Health insurance charges	From Baseline to 6 months	From Baseline to 6 months
	• Pharmacy prices

^a)The bereaved is the primary caregiver, ^b)Only patients with participating relatives, ^c)The National Patient Register, Health Insurance Registry, Medicine Databases.