Table 3.

Volumes of brain structures (% of ICV) in OSA patients and controls. Means ± standard deviations are reported; P-values refer to 2-tailed Student’s T-test.

Structure		Patients (n=16)	Controls (n=14)	P-value
Brain parenchymal fraction (BPF) a		83.7 ± 2.6	85.3 ± 2.3	0.068
Total gray matter (GM) a		41.5 ± 3.4	43.5 ± 2.9	0.09
Total white matter (WM) a		42.1 ± 1.4	41.8 ± 1.1	0.46
White matter hyperintensities (WMH) a		0.167 ± 0.402	0.109 ± 0.101	0.60
Cortical GM volume b	Left	14.7 ± 2.8	16.8 ± 1.1	0.015
	Right	14.5 ± 3.1	16.8 ± 1.0	0.012
	Total	29.2 ± 5.9	33.6 ± 2.1	0.012
Hippocampus b	Left	0.288 ± 0.054	0.290 ± 0.031	0.94
	Right	0.279 ± 0.040	0.312 ± 0.033	0.024
Amygdala b	Left	0.115 ± 0.016	0.119 ± 0.013	0.53
	Right	0.123 ± 0.015	0.128 ± 0.016	0.38
Caudate b	Left	0.210 ± 0.046	0.246 ± 0.040	0.030
	Right	0.218 ± 0.036	0.244 ± 0.030	0.044
Putamen b	Left	0.338 ± 0.054	0.343 ± 0.042	0.77
	Right	0.318 ± 0.045	0.327 ± 0.034	0.56
Thalamus b	Left	0.445 ± 0.052	0.478 ± 0.044	0.07
	Right	0.444 ± 0.055	0.466 ± 0.054	0.28
Cerebellum b		7.27 ± 1.78	7.83 ± 2.03	0.43

^aVolume obtained from 3D-Slicer brain segmentation

^bVolume obtained from FreeSurfer brain segmentation