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Deiodination of 125I-p5 results in free 125I in the circulation and uptake in the stomach and thyroid in WT mice. SDS-PAGE phosphor images and quantification of blood (A & B) and kidney (C & D) indicate changes in 125I-p5 peptide (arrow; ○) and free 125I (arrowhead; •) over 60 min. (E) SPECT/CT image of WT mouse 30 min post injection of 95 μCi of 125I indicating uptake in the stomach (St) and thyroid (T).
