Table 1. Characteristics of the Study Population.
| HIV Seropositive | HIV Seronegative | p-value* | CT with contrast | Non-contrast CT only | p-value† | |
|---|---|---|---|---|---|---|
| N | 579 | 353 | 706 | 226 | ||
| Age (years) | 53.4(6.5) | 55.9(7.3) | <0.001 | 54.0(7.0) | 55.3(6.6) | 0.01 |
| Race | <0.001 | 0.62 | ||||
| Caucasian (%) | 54.1 | 68.6 | 59.1 | 61.1 | ||
| African-American (%) | 32.8 | 23.8 | 29.3 | 29.6 | ||
| Hispanic/Other (%) | 13.1 | 7.6 | 11.6 | 9.3 | ||
| Hypertension (%) | 49.0 | 47.7 | 0.70 | 46.5 | 54.8 | 0.03 |
| Hypertension medications (%) | 35.3 | 33.6 | 0.60 | 31.7 | 43.8 | 0.001 |
| Diabetes (%) | 13.7 | 10.0 | 0.11 | 10.5 | 17.9 | 0.004 |
| Diabetes medications (%) | 9.2 | 7.4 | 0.35 | 7.3 | 12.4 | 0.02 |
| Tobacco use | 0.004 | 0.19 | ||||
| Never smoker (%) | 25.8 | 24.6 | 25.0 | 26.5 | ||
| Current smoker (%) | 30.8 | 22.0 | 26.2 | 31.4 | ||
| Former smoker (%) | 43.4 | 53.4 | 48.8 | 42.2 | ||
| Body Mass Index (kg/m2) | 26.1(4.4) | 27.5(4.9) | <0.001 | 26.6(4.5) | 26.7(5) | 0.75 |
| Glucose (mg/dL) | 102.8(25) | 101.9(31.9) | 0.16 | 101.0(24.3) | 107.2(36.7) | 0.01 |
| Insulin (μIU/mL) | 17.3(14) | 15.1(12.2) | <0.001 | 15.4(9.9) | 19.9(20.7) | 0.005 |
| Total Cholesterol (mg/dL) | 188.3(43.1) | 191.6(36.4) | 0.13 | 189.2(39.1) | 190.6(45.5) | 0.64 |
| LDL Cholesterol (mg/dL) | 105.9(35.8) | 112.3(32.2) | 0.002 | 109.4(34.4) | 105.0(35.0) | 0.03 |
| HDL Cholesterol (mg/dL) | 48.2(16.0) | 52.7(16.3) | <0.001 | 49.8(15.9) | 50.3(17.3) | 0.97 |
| Triglycerides (mg/dL) | 174.6(131.1) | 127.6(78.2) | <0.001 | 150.8(101.7) | 176.5(153.0) | 0.054 |
| Lipid lowering medications (%) | 36.3 | 29.7 | 0.04 | 33.4 | 34.8 | 0.70 |
| Serum Creatinine (mg/dL) | 1.1(0.5) | 1.0(0.2) | 0.03 | 1.0(0.2) | 1.3(0.7) | <0.001 |
| Among HIV Seropositive | N = 579 | N = 422 | N =157 | |||
| Viral Load undetectable, < 50 copies/mL (%) | 80.9 | - | 79.9 | 83.6 | 0.33 | |
| Viral Load (copies/mL)** | 565(150-9070) | - | 611(125-10053) | 537(189-5939) | 0.97 | |
| CD4+ T-cell count (cells/mm3) | 599(423-749) | - | 600(431-749) | 579(408-748) | 0.51 | |
| CD4+ T-cell count nadir (cells/mm3) | 243(133-331) | - | 253(155-339) | 206(95-312) | 0.006 | |
| Initiated HAART (%) | 95.9 | - | 95.3 | 97.5 | 0.24 | |
| Duration of HAART (years) | 12.5(8.8-14.1) | - | 12.2(8.5-14) | 13.1(9.7-14.4) | 0.03 | |
| History of AIDS (%) | 13.8 | - | 10.9 | 21.7 | 0.001 |
Data are presented stratified by HIV serostatus for the entire cohort and then stratified by whether or not a CT with contrast was performed. Laboratory results represent fasting levels. Data are reported as mean (standard deviation) or percentage or median (1st quartile – 3rd quartile). P values are unadjusted.
*
P value comparing seropositive and seronegative values.
†
P value comparing CT with contrast versus non-contrast only values.
**
Among 108 HIV+ men with detectable viral load (>50 copies/mL)