Table 4. Associations between Epicardial Adipose Tissue Volume and Presence of Coronary Artery Plaque (Plaque scores > 0 vs. 0).
Coronary artery calcium N= 931 Prevalence=53% |
Non-calcified plaque N= 706 Prevalence=60% |
Calcified plaque N= 706 Prevalence=37% |
Mixed plaque N= 706 Prevalence=34% |
Any plaque N= 706 Prevalence=77% |
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OR (95% CI) | p-value | OR (95% CI) | p-value | OR (95% CI) | p-value | OR (95% CI) | p-value | OR (95% CI) | p-value | |
|
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Model 1 | 1.04 (1.02,1.07) |
0.003 | 1.06 (1.03,1.1) |
<0.001 | 1.03 (1.002,1.07) |
0.04 | 1.02 (0.99,1.06) |
0.17 | 1.09 (1.04,1.14) |
<0.001 |
Model 2 | 1.01 (0.98,1.04) |
0.47 | 1.06 (1.02,1.1) |
0.001 | 1.01 (0.97,1.04) |
0.62 | 1.00 (0.97,1.04) |
0.84 | 1.07 (1.02,1.12) |
0.006 |
Model 3 | 1.01 (0.98,1.04) |
0.55 | 1.07 (1.03,1.11) |
0.001 | 1.00 (0.96,1.04) |
0.98 | 1.01 (0.98,1.05) |
0.49 | 1.06 (1.01,1.12) |
0.02 |
Model 4 | 1.02 (0.98,1.06) |
0.32 | 1.07 (1.02,1.11) |
0.002 | 1.00 (0.96,1.04) |
0.87 | 1.01 (0.97,1.05) |
0.76 | 1.07 (1.01,1.13) |
0.02 |
OR= odds ratio (per 10 units increase in Epicardial Adipose Tissue Volume); CI= confidence interval. Model 1- Adjusted for age, race and HIV serostatus; Model 2- Model 1 plus CAD risk factors; Model 3- Model 2 plus body mass index; Model 4- Model 2 plus abdominal visceral adipose volume. CAD risk factors include use of antihypertensive medications, systolic blood pressure (among those not on antihypertensive medications), use of diabetes medications, fasting glucose (among those not on diabetes medications), use of lipid medication use, triglyceride levels (among those not on lipid medications) and smoking (cumulative pack years)