Table 1.
Baseline characteristics
| Characteristics | Bivalirudin (N = 1089) n/N (%) |
Heparins + routine GPI (N = 649) n/N (%) |
Heparins + bailout GPI (N = 460) n/N (%) |
|---|---|---|---|
| Bailout GPIa | 83/1046 (7.9) | N/A | 117/460 (25.4) |
| Age, median (IQR), years | 61 (52, 71) | 61 (52, 71) | 62 (53, 73) |
| Age >65 years | 394 (36.2) | 245 (37.8) | 189 (41.1) |
| Female | 275 (25.3) | 144 (22.2) | 104 (22.6) |
| Diabetes | 127 (11.7) | 89/648 (13.7) | 80 (17.4) |
| Current smoker (within past 30 days) | 453 (41.6) | 271/648 (41.8) | 201 (43.7) |
| Hypertension† | 459 (42.2) | 261/648 (40.3) | 243 (52.8) |
| Previous myocardial infarction | 80 (7.4) | 65/648 (10.0) | 48 (10.4) |
| Previous PTCA/PCI | 97 (8.9) | 57/648 (8.8) | 51 (11.1) |
| Previous CABG | 18 (1.7) | 14/648 (2.2) | 15 (3.3) |
| Hyperlipidaemiab | 398 (36.6) | 222/648 (34.3) | 195 (42.4) |
| Killip class II–IV† | 77/996 (7.7) | 27/568 (4.8) | 42/432 (9.7) |
| Creatinine clearance ≤60 mL/min† | 147/1001 (14.7) | 81/617 (13.1) | 84/381 (22.0) |
| Creatinine clearance >60 mL/min | 854/1001 (85.3) | 536/617 (86.9) | 297/381 (78.0) |
| Anaemia | 129/987 (13.1) | 86/606 (14.2) | 62/383 (16.2) |
CABG, coronary artery bypass graft surgery; GPI, glycoprotein IIb/IIIa inhibitor; IQR, interquartile range; N/A, not applicable; PCI, percutaneous coronary intervention; PTCA, percutaneous transluminal coronary angioplasty.
aData are provided for patients who were eligible for bailout use of a GPI (i.e. those who did not receive the drug routinely).
bKnown hyperlipidaemia or on lipid-lowering drugs.
†P < 0.05.