Table 4a.

Net Reclassmcation Improvement (NRI) table comparing the MESA-HNR score versus the Framingham Risk Score for incident coronary heart disease events.

	Risk in MESA-HNR Score
Risk in Refit FRS Score	<6%	6–20%	≥20%	Overall	Reclassified as Higher Risk	Reclassified as Lower Risk
<6%
No. of participants	623	131	12	766
No. of events	16	7	2	25	9	NA
No. of non-events	607	124	10	741	134	NA
6–20%
No. of participants	272	241	54	567
No. of events	15	28	16	59	16	15
No. of non-events	257	213	38	508	38	257
≥20%
No. of participants	1	5	4	10
No. of events	0	0	1	1	NA	0
No. of non-events	1	5	3	9	NA	6
Overall
No. of participants	896	377	70	1343
No. of events	31	35	19	85	25	15
No. of non-events	865	342	51	1258	172	263

n	NRI*	Standard Error NRI	P-value NRI
1343	0.190	0.076	0.013

^*NRI= Net Reclassification Index