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. Author manuscript; available in PMC: 2015 Apr 1.
Published in final edited form as: J Immunol. 2014 Aug 25;193(7):3717–3725. doi: 10.4049/jimmunol.1401307

Figure 3.

Figure 3

Skin ILC2 responses are dependent on basophils. (A) Skin basophils and associated (B) frequencies and total cell numbers in WT mice treated with EtOH or MC903 and BaS-TRECK (BaS) mice treated with MC903. (C) Skin ILC2s and associated (D) frequencies and total cell numbers and (E) histopathology, (F) histology score and (G) ear thickness on day 7 in WT mice treated with EtOH or MC903 and BaS mice treated with MC903. (H) Skin ILC2s and associated (I) frequencies and (J) histopathology on day 4 following intradermal (i.d.) injection of PBS or sort-purified basophils from TSLP cDNA-injected WT mice. Scale bars, 50 μm. Cell frequencies are noted as a percentage of Lin− cells. Data are representative of three independent experiments; n = 3-4 mice per group per experiment. Actual P-values are indicated.