Figure 3.
Impaired regulation of 3a: cerebral oxygen saturation (rSO2), cerebral fractional tissue oxygen extraction (FTOE), mean arterial pressure (MAP) and 3b: amplitude EEG (aEEG) during 6 hours of hypothermia (left) and re-warming (right) . Polynomial line fit was used to show the trend of cerebral and systemic hemodynamic variables over time. Note the persistently increased rSO2 of 95% with a concurrent FTOE of <5%. aEEG revealed a pattern of low voltage discontinuous activity with no sleep wake cycles. Infant had seizures four hours after initiation of re-warming (red arrow). This infant had an abnormal outcome (Bayley III at 24 months: cognitive score 65, motor score 82).