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. Author manuscript; available in PMC: 2015 Oct 1.
Published in final edited form as: J Immunol. 2014 Aug 29;193(7):3816–3824. doi: 10.4049/jimmunol.1303256

Figure 4.

Figure 4

Absence of recipient CCR5 results in exaggerated CD8 T cell responses to single class II MHC-disparate bm12 renal allografts. Groups of wild type C57BL/6 and B6.CCR5-deficient mice received bm12 renal allografts. On day 14 post-transplant CD4 and CD8 T cells were purified from each of the recipient spleens and the frequency of bm12 donor-reactive CD4 and CD8 T cells producing IFN-γ was quantified by ELISPOT assay. The results indicate the mean number of spots for splenic CD4 or CD8 T cells from 4 individual mice per group ± SEM.*p < 0.05