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. Author manuscript; available in PMC: 2015 Oct 1.
Published in final edited form as: J Immunol. 2014 Aug 29;193(7):3816–3824. doi: 10.4049/jimmunol.1303256

Figure 5.

Figure 5

Rejection of single class II MHC-disparate bm12 renal allografts by B6.CCR5-deficient recipients is not mediated by antibody. (A) Groups of wild type C57Bl/6, B6.CCR5−/− and B6.CCR5−/−µMT−/− mice received single class II MHC disparate renal grafts from B6.H-2bm12 donors and allograft survival was monitored. (B) Grafts were harvested from B6.CCR5−/−µMT−/− recipients at the time of rejection and formalin-fixed/paraffin embedded sections were stained with hematoxylin and eosin and frozen sections were stained with antibodies to detect CD4 and CD8 T cells. Magnification x400.