Table 1.
CMRO2 values reported in literature.
| Study | Method | Number of subjects |
Gestational age (weeks) |
Subject condition |
Yv (%) | CBF (ml/100g/min) |
CMRO2 (μmol/100g/min) |
|---|---|---|---|---|---|---|---|
| Skov et al, 1993 [13] | NIRS | 32 | 26 – 39 | Asphyxiated; RDS | 53.44±15.36 (preterm) | 12.6±6.4 (preterm) | 44.7±17.9 (preterm) |
| 67.30±9.38 (term) | 26.5±17.9 (term) | 62.6±35.8 (term) | |||||
| Altman et al, 1993 [9] | PET | 11 | 26 – 41 | HIE and other conditions | - | 21.6±21.0 | 21.4±16.4 |
| Yoxall and weindling, 1998 [14] | NIRS | 20 | 24 – 41 | Seizure and other conditions | 64.6 (76.1 – 46.8) | 9.3 (4.5 – 28.3) | 23.1 (8.6 – 78.5) |
| Elwell et al, 2005 [12] | NIRS | 9 | 23 – 37 | Ventilatory support | - | - | 45.9±12.3 |
| Liu et al, 2014[24] | MRI | 12 | 35 – 42 | Healthy | 62.6±8.3 | 13.4±4.2 | 38.3±17.7 |
| Jain et al, 2014[33] | MRI | 33 | 38 – 40 | CHD | 55.2 (49.3 – 60.2) | 9.7 (7.5 – 15.1) | 23.2 (17.8 – 35.2) |
| De Vis et al, 2014[32] | MRI | 51 | 28 – 52 | Healthy, HIE and other diagnosis | 52±12 (healthy) | 14±3 (healthy) | 30±6 (healthy) |
| 65±13 (HIE) | 12±4 (HIE) | 24±12 (HIE) |
NIRS, near infrared spectroscopy; PET, positron emission tomography; MRJ, magnetic resonance imaging; RDS, Respiratory distress syndrome; HIE, Hypoxic-ischemic encephalopathy; CHD, Congenital heart disease.